Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | phosphatidylethanolamine, monomethyl-phosphatidylethanolamine and dimethyl-phosphatidylethanolamine compete for a common active site | Rattus norvegicus | |
S-adenosyl-L-homocysteine | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0136 | - |
S-adenosylmethionine | reaction with phosphatidyl-N,N-dimethylethanolamine | Rattus norvegicus | |
0.0296 | - |
S-adenosylmethionine | reaction with phosphatidylethanolamine | Rattus norvegicus | |
0.0397 | - |
S-adenosylmethionine | reaction with phosphatidyl-N-monomethylethanolamine | Rattus norvegicus | |
0.74 | - |
phosphatidyl-N-methylethanolamine | - |
Rattus norvegicus | |
2.12 | - |
phosphatidyl-N,N-dimethylethanolamine | - |
Rattus norvegicus | |
5 | - |
phosphatidylethanolamine | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine | phospholipid substrates and products are the first to bind and the last to dissociate from the active site | Rattus norvegicus | 2 S-adenosyl-L-homocysteine + phosphatidylcholine | - |
? | |
2 S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine | ordered bi-bi mechanism | Rattus norvegicus | 2 S-adenosyl-L-homocysteine + phosphatidylcholine | - |
? | |
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine | - |
Rattus norvegicus | S-adenosyl-L-methionine + phosphatidylethanolamin | - |
? | |
S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine | phospholipid substrates and products are the first to bind and the last to dissociate from the active site | Rattus norvegicus | S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine | - |
? | |
S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine | ordered bi-bi mechanism | Rattus norvegicus | S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine | - |
? | |
S-adenosyl-L-methionine + phosphatidylethanolamine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.138 | - |
S-adenosyl-L-homocysteine | reaction with phosphatidyl-N-monomethylethanolamine | Rattus norvegicus | |
0.2775 | - |
S-adenosyl-L-homocysteine | reaction with phosphatidylethanolamine | Rattus norvegicus |