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Literature summary for 2.1.1.166 extracted from

  • Arai, T.; Ishiguro, K.; Kimura, S.; Sakaguchi, Y.; Suzuki, T.; Suzuki, T.
    Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly (2015), Proc. Natl. Acad. Sci. USA, 112, E4707-E4716.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.166

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + uridine2552 in 23S rRNA Escherichia coli
-
 S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA
-
 ?
S-adenosyl-L-methionine + uridine2552 in 23S rRNA Escherichia coli BW25113
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 S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli BW25113
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + uridine2552 in 23S rRNA
-
 Escherichia coli S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA
-
 ?
S-adenosyl-L-methionine + uridine2552 in 23S rRNA
-
 Escherichia coli BW25113 S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA
-
 ?

Synonyms

Synonyms Comment Organism
FTSJ
-
 Escherichia coli
RlmE
-
 Escherichia coli
RrmJ
-
 Escherichia coli

General Information

General Information Comment Organism
malfunction enzyme deletion results in slow growth and accumulation of the 45S particle Escherichia coli
physiological function the enzyme is an assembly factor that acts at a late step of 50S formation Escherichia coli