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Literature summary for 2.1.1.160 extracted from

  • Kato, M.; Kitao, N.; Ishida, M.; Morimoto, H.; Irino, F.; Mizuno, K.
    Expression for caffeine biosynthesis and related enzymes in Camellia sinensis (2010), Z. Naturforsch. C, 65c, 245-256.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine Camellia sinensis
-
S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine
-
?
S-adenosyl-L-methionine + 7-methylxanthine Camellia sinensis
-
S-adenosyl-L-homocysteine + 3,7-dimethylxanthine
-
?

Organism

Organism UniProt Comment Textmining
Camellia sinensis
-
cv. Yabukita, TCS gene
-

Source Tissue

Source Tissue Comment Organism Textmining
flower TCS transcripts content remains constant throughout fl ower development Camellia sinensis
-
leaf TCS transcripts content is highest in young leaves and declines markedly during leaf development Camellia sinensis
-
additional information expression profi le of the tea caffeine synthasegene in developing leaves and fl owers by northern blot RNA analysis Camellia sinensis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine
-
Camellia sinensis S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine
-
?
S-adenosyl-L-methionine + 7-methylxanthine
-
Camellia sinensis S-adenosyl-L-homocysteine + 3,7-dimethylxanthine
-
?

Synonyms

Synonyms Comment Organism
TCS
-
Camellia sinensis
tea caffeine synthase
-
Camellia sinensis

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Camellia sinensis

Expression

Organism Comment Expression
Camellia sinensis drought stress suppresses TCS gene expression in leaves down
Camellia sinensis environmental stresses other than heavy metal stress and plant hormone treatments have no effect on the expression of TCS gene additional information
Camellia sinensis TCS transcript increases slightly on supply of a nitrogen source up

General Information

General Information Comment Organism
metabolism caffeine synthase catalyzes the S-adenosyl-L-methionine-dependent N-3- and N-1-methylation of the purine base to form caffeine, the last step in the purine alkaloid biosynthetic pathway. Pathways for the biosynthesis of caffeine and phenylpropanoids, overview Camellia sinensis
additional information regulation of TCS gene expression Camellia sinensis