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Literature summary for 2.1.1.160 extracted from

  • Ogita, S.; Uefuji, H.; Morimoto, M.; Sano, H.
    Application of RNAi to confirm theobromine as the major intermediate for caffeine biosynthesis in coffee plants with potential for construction of decaffeinated varieties (2004), Plant Mol. Biol., 54, 931-941.
    View publication on PubMed
Search for more literature for 2.1.1.160

Cloned(Commentary)

Cloned (Comment) Organism
expression analysis Coffea canephora
gene DXMT1, DNA and amino acid sequence determination and analysis, expression analysis Coffea arabica

Protein Variants

Protein Variants Comment Organism
additional information reduction of the second enzyme of the pathway, 7-methylxanthine methyltransferase, EC 2.1.1.159, leads to reduced DXMT1 expression Coffea canephora
additional information reduction of the second enzyme of the pathway, 7-methylxanthine methyltransferase, EC 2.1.1.159, leads to reduced DXMT1 expression Coffea arabica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine Coffea canephora last step in caffeine biosynthesis pathway S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir
S-adenosyl-L-methionine + 3,7-dimethylxanthine Coffea arabica last step in caffeine biosynthesis pathway S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir

Organism

Organism UniProt Comment Textmining
Coffea arabica Q8H0D2 gene CaDXMT1; var. caturra
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Coffea canephora
-
 var. conilon
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf young Coffea canephora
-
leaf young Coffea arabica
-
additional information method development for somatic embryogenesis, overview Coffea canephora
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additional information method development for somatic embryogenesis, overview Coffea arabica
-
seedling derived from somatic embryogenesis Coffea canephora
-
seedling derived from somatic embryogenesis Coffea arabica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine
-
 Coffea canephora S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir
S-adenosyl-L-methionine + 3,7-dimethylxanthine
-
 Coffea arabica S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir
S-adenosyl-L-methionine + 3,7-dimethylxanthine last step in caffeine biosynthesis pathway Coffea canephora S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir
S-adenosyl-L-methionine + 3,7-dimethylxanthine last step in caffeine biosynthesis pathway Coffea arabica S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir

Synonyms

Synonyms Comment Organism
3,7-dimethylxanthine methyltransferase
-
 Coffea canephora
3,7-dimethylxanthine methyltransferase
-
 Coffea arabica
DXMT1
-
 Coffea canephora
DXMT1
-
 Coffea arabica