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Literature summary for 2.1.1.160 extracted from

  • Ogawa, M.; Herai, Y.; Koizumi, N.; Kusano, T.; Sano, H.
    7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties (2001), J. Biol. Chem., 276, 8213-8218.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene CaMTL1, cDNA library construction, DNA and amino acid sequence determination and analysis, sequence comparison with other species Coffea arabica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine Coffea arabica last step in caffeine biosynthesis pathway S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir

Organism

Organism UniProt Comment Textmining
Coffea arabica Q9AVJ9 gene CaMTL1; var. caturra
-

Source Tissue

Source Tissue Comment Organism Textmining
bud
-
Coffea arabica
-
leaf old and young Coffea arabica
-
additional information wide tissue distribution Coffea arabica
-
root
-
Coffea arabica
-
stem
-
Coffea arabica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine
-
Coffea arabica S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir
S-adenosyl-L-methionine + 3,7-dimethylxanthine last step in caffeine biosynthesis pathway Coffea arabica S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine i.e. caffeine ir

Synonyms

Synonyms Comment Organism
caffeine synthase
-
Coffea arabica
CS
-
Coffea arabica
TCS1
-
Coffea arabica