Crystallization (Comment) | Organism |
---|---|
structure of ThyX in complex with nonsubstrate analog inhibitor (2R)-2-[(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)sulfanyl]propanoic acid | Thermotoga maritima |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R)-2-[(3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)sulfanyl]propanoic acid | 6% inhibition at 0.1 mM | Thermotoga maritima |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0046 | - |
dUMP | pH not specified in the publication, temperature not specified in the publication | Thermotoga maritima | |
0.13 | - |
NADPH | pH not specified in the publication, temperature not specified in the publication | Thermotoga maritima |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermotoga maritima | Q9WYT0 | - |
- |
Thermotoga maritima DSM 3109 | Q9WYT0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ | - |
Thermotoga maritima | dTMP + tetrahydrofolate + NADP+ | - |
? | |
5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ | - |
Thermotoga maritima DSM 3109 | dTMP + tetrahydrofolate + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ThyX | - |
Thermotoga maritima |