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Literature summary for 2.1.1.148 extracted from

  • Gattis, S.G.; Palfey, B.A.
    Direct observation of the participation of flavin in product formation by thyX-encoded thymidylate synthase (2005), J. Am. Chem. Soc., 127, 832-833.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + dUMP + FADH2 the flavin is oxidized after dUMP reacts with 5,10-methylenetetrahydrofolate Campylobacter jejuni dTMP + tetrahydrofolate + FAD
-
?

Synonyms

Synonyms Comment Organism
thyX-encoded thymidylate synthase
-
Campylobacter jejuni

Cofactor

Cofactor Comment Organism Structure
FAD the flavin is oxidized after dUMP reacts with 5,10-methylenetetrahydrofolate Campylobacter jejuni
FADH2 the flavin is oxidized after dUMP reacts with 5,10-methylenetetrahydrofolate Campylobacter jejuni