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Literature summary for 2.1.1.140 extracted from

  • Zhao, W.; Shen, C.; Zhu, J.; Ou, C.; Liu, M.; Dai, W.; Liu, X.; Liu, J.
    Identification and characterization of methyltransferases involved in benzylisoquinoline alkaloids biosynthesis from Stephania intermedia (2019), Biotechnol. Lett., 42, 461-469 .
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0746
-
(R)-coclaurine pH 9, 37°C Stephania intermedia
0.0922
-
(R)-coclaurine pH 9, 37°C Stephania intermedia
0.0971
-
(R)-coclaurine pH 9, 37°C Stephania intermedia

Organism

Organism UniProt Comment Textmining
Stephania intermedia A0A5P9PAN8 isoform CNMT1
-
Stephania intermedia A0A5P9PAQ9 isoform CNMT3
-
Stephania intermedia A0A5P9PAT6 isoform CNMT2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + (R)-coclaurine
-
Stephania intermedia S-adenosyl-L-homocysteine + (R)-N-methylcoclaurine
-
?
S-adenosyl-L-methionine + (R)-N-methylcoclaurine
-
Stephania intermedia S-adenosyl-L-homocysteine + (R)-magnocurarine
-
?

Subunits

Subunits Comment Organism
? x * 41080, calculated from sequence Stephania intermedia
? x * 41600, calculated from sequence Stephania intermedia

Synonyms

Synonyms Comment Organism
CNMT
-
Stephania intermedia

pI Value

Organism Comment pI Value Maximum pI Value
Stephania intermedia calculated from sequence
-
6
Stephania intermedia calculated from sequence
-
6.4