Protein Variants | Comment | Organism |
---|---|---|
D113R | mutation abrogate nuclear localization | Komagataella pastoris |
R742A | nuclear localization is abrogated by the deletion of 107 C-terminal amino acids or the R742A mutation | Komagataella pastoris |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | nuclear localization is abrogated by the deletion of 107 C-terminal amino acids or the R742A mutation | Komagataella pastoris | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Komagataella pastoris | A0A1B2JIW1 | - |
- |
Subunits | Comment | Organism |
---|---|---|
More | dimer-like configuration in which Arg-742 of a monomer forms a salt bridge with Asp-113 of another monomer, in silico analysis | Komagataella pastoris |
Synonyms | Comment | Organism |
---|---|---|
Met6 | - |
Komagataella pastoris |
General Information | Comment | Organism |
---|---|---|
physiological function | a strain carrying a deletion of the MET6 gene exhibits methionine as well as adenine auxotrophy. Methionine synthase targeted to the cytoplasm via a heterologous nuclear export signal, is expressed at very low levels and is unable to reverse methionine and adenine auxotrophy of a Met6 deletion strain | Komagataella pastoris |