Literature summary for 2.1.1.13 extracted from

Bassila, C.; Ghemrawi, R.; Flayac, J.; Froese, D.S.; Baumgartner, M.R.; Gueant, J.L.; Coelho, D.
Methionine synthase and methionine synthase reductase interact with MMACHC and with MMADHC (2017), Biochim. Biophys. Acta, 1863, 103-112 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q99707	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	expression of both active 140 kDa form and the inactive truncated 124 kDa isoform	Homo sapiens	-
Hep-G2 cell	expression of both active 140 kDa form and the inactive truncated 124 kDa isoform	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	MMACHC plays an important role in the interaction of methionine synthase with methionine synthase reductase MSR. In a multifunctional protein complex containing at least MMACHC, methionine synthase and MSR, the presence of each protein would strengthen the interactions between the two others	Homo sapiens

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Release 2023.1 (January 2023)