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Literature summary for 2.1.1.13 extracted from

  • Cheng, F.W.; Shane, B.; Stokstad, E.L.R.
    Pentaglutamate derivatives of folate as substrates for rat liver tetrahydropteroylglutamate methyltransferase and 5,10-methylenetetrahydrofolate reductase (1975), Can. J. Biochem., 53, 1020-1027.
No PubMed abstract available
Search for more literature for 2.1.1.13

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
 5-Methyl-5,6,7,8-tetrahydropteroylpentaglutamate
-
 Rattus norvegicus
0.013
-
 5-methyl-5,6,7,8-tetrahydropteroylmonoglutamate
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-methyl-5,6,7,8-tetrahydropteroylpentaglutamate + L-homocysteine
-
 Rattus norvegicus ?
-
 ?
N5-methyltetrahydrofolate + L-homocysteine
-
 Rattus norvegicus tetrahydrofolate + L-methionine
-
 ?
N5-methyltetrahydropteroylmonoglutamate + L-homocysteine
-
 Rattus norvegicus tetrahydropteroylmonoglutamate + L-methionine
-
 ?
N5-methyltetrahydropteroylpentaglutamate + L-homocysteine
-
 Rattus norvegicus tetrahydropteroylpentaglutamate + L-methionine
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Rattus norvegicus