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Literature summary for 2.1.1.113 extracted from

  • Kumar, S.; Karmakar, B.C.; Nagarajan, D.; Mukhopadhyay, A.K.; Morgan, R.D.; Rao, D.N.
    N4-cytosine DNA methylation regulates transcription and pathogenesis in Helicobacter pylori (2018), Nucleic Acids Res., 46, 3429-3445 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Helicobacter pylori O25921
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Helicobacter pylori 26695 O25921
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Synonyms

Synonyms Comment Organism
HP_1368
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Helicobacter pylori

General Information

General Information Comment Organism
physiological function enzyme recognizes the 5'TCTTC3'x02 sequence and methylates the first cytosine residue. A deletion strain displays lower adherence to host gastric adenocarcinoma cells and reduced potential to induce inflammation and apoptosis. The deletion strain exhibits reduced capacity for natural transformation, and a total of 102 genes belonging to virulence, ribosome assembly and cellular components are differentially expressed Helicobacter pylori