Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21-Codon-Plus cells | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amodiaquine | complete inhibition at 0.025 mM | Plasmodium falciparum | |
dodecyltrimethylammonium | 25% inhibition at 0.5 mM | Plasmodium falciparum | |
hexadecyltrimethylammonium | about 50% inhibition at 0.1 mM | Plasmodium falciparum | |
miltefosine | about 60% inhibition at 0.1 mM, complete loss of activity at 0.15 mM | Plasmodium falciparum | |
additional information | not inhibited by 2,3-dichloro-methylbenzyl-amine, chloroquine, and dodecyltrimethylammonium at concentrations up to 0.1 mM | Plasmodium falciparum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography, gel filtration | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 S-adenosyl-L-methionine + phosphoethanolamine | - |
Plasmodium falciparum | 3 S-adenosyl-L-homocysteine + phosphocholine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphoethanolamine methyltransferase | - |
Plasmodium falciparum |
PMT | - |
Plasmodium falciparum |