Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Relomycin | - |
Streptomyces fradiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.029 | - |
S-adenosyl-L-methionine | - |
Streptomyces fradiae | |
0.033 | - |
macrocin | - |
Streptomyces fradiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | stimulated by cobalt chloride | Streptomyces fradiae | |
Fe2+ | stimulated by iron (II) sulfate | Streptomyces fradiae | |
Mg2+ | stimulated by magnesium sulfate | Streptomyces fradiae | |
Mn2+ | stimulated by manganese sulfate | Streptomyces fradiae | |
Zn2+ | stimulated by zinc sulfate | Streptomyces fradiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + macrocin | Streptomyces fradiae | terminal and main rate-limiting step in tylosin biosynthesis | S-adenosylhomocysteine + tylosin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces fradiae | - |
- |
- |
Storage Stability | Organism |
---|---|
4°C, enzyme is unstable, about 30% activity remains after 3 h | Streptomyces fradiae |
4°C, very stable for 3 h in presence of 10% ethanol | Streptomyces fradiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + macrocin | - |
Streptomyces fradiae | S-adenosyl-L-homocysteine + tylosin | - |
? | |
S-adenosyl-L-methionine + macrocin | terminal and main rate-limiting step in tylosin biosynthesis | Streptomyces fradiae | S-adenosylhomocysteine + tylosin | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
- |
Streptomyces fradiae |