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Literature summary for 2.1.1.1 extracted from

  • Sartini, D.; Santarelli, A.; Rossi, V.; Goteri, G.; Rubini, C.; Ciavarella, D.; Lo Muzio, L.; Emanuelli, M.
    Nicotinamide N-methyltransferase upregulation inversely correlates with lymph node metastasis in oral squamous cell carcinoma (2007), Mol. Med., 13, 415-421.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.1

Application

Application Comment Organism
pharmacology NNMT as potential biomarker and therapeutic target Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P40261
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Source Tissue

Source Tissue Comment Organism Textmining
oral mucosa
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 Homo sapiens
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oral squamous cell carcinoma cell line
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 Homo sapiens
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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 expression levels of NNMT in oral squamous cell carcinoma (OSCC), quantitative real-time PCR, Western-Blot and immunohistochemical analyses, upregulation in tumor cells, correlation between NNMT upregulation and favorable prognosis of oral squamous cell carcinoma patients Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + nicotinamide NNMT potential as tumor marker Homo sapiens S-adenosyl-L-homocysteine + 1-methylnicotinamide
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 ?

Synonyms

Synonyms Comment Organism
NNMT
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 Homo sapiens