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Literature summary for 1.8.4.8 extracted from

  • Schwenn, J.D.; Krone, F.A.; Husmann, K.
    Yeast PAPS reductase: properties and requirements of the purified enzyme (1988), Arch. Microbiol., 150, 313-319.
    View publication on PubMed
Search for more literature for 1.8.4.8

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0006
-
 thioredoxin
-
 Saccharomyces cerevisiae
0.0014
-
 thioredoxin
-
 Saccharomyces cerevisiae
0.019
-
 5-Phosphoadenosine 3-phosphosulfate with thioredoxin from Saccharomyces cerevisiae as cosubstrate Saccharomyces cerevisiae
0.021
-
 5-Phosphoadenosine 3-phosphosulfate with thioredoxin from E. coli as cosubstrate Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Reaction

Reaction Comment Organism Reaction ID
adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin from the kinetic data it is concluded that the enzyme follows an ordered mechanism with thioredoxin as the first substrate followed by 5-phosphoadenosine 3-phosphosulfate as the second Saccharomyces cerevisiae
a

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
44.13
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + thioredoxin thioredoxin from Escherichia coli Saccharomyces cerevisiae adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide
-
 r
3'-phosphoadenylyl sulfate + thioredoxin thioredoxin from Saccharomyces cerevisiae Saccharomyces cerevisiae adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide
-
 r
5-Phosphoadenosine 3-phosphosulfate + reduced thioredoxin
-
 Saccharomyces cerevisiae adenosine-3',5'-bisphosphate + oxidized thioredoxin + sulfite
-
 ?