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Literature summary for 1.8.4.2 extracted from
- Role of cysteine-58 and cysteine-95 residues in the thiol di-sulfide oxidoreductase activity of macrophage migration inhibitory factor-2 of Wuchereria bancrofti (2016), Acta Trop., 153, 14-20 .
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| homology modeling.Csteine residues, Cys58 and Cys95 come in close proximity in the tertiary structure with pKa value 9. The residues are involved in the disulfide oxidoreductase catalytic activity | Wuchereria bancrofti |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C58S | complete loss of oxidoreductase activtiy | Wuchereria bancrofti |
| C95S | complete loss of oxidoreductase activtiy | Wuchereria bancrofti |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Wuchereria bancrofti | A0A088FMA5 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| insulin disulfide + dithiothreitol | - |
Wuchereria bancrofti | insulin + dithiothreitol disulfide | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 17000, SDS-PAGE | Wuchereria bancrofti |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mcrophage migration inhibitory factor-2 | - |
Wuchereria bancrofti |
| Mif-2 | - |
Wuchereria bancrofti |
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Release 2023.1 (January 2023)
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