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Literature summary for 1.8.4.12 extracted from

  • Aachmann, F.L.; Sal, L.S.; Kim, H.Y.; Marino, S.M.; Gladyshev, V.N.; Dikiy, A.
    Insights into function, catalytic mechanism, and fold evolution of selenoprotein methionine sulfoxide reductase B1 through structural analysis (2010), J. Biol. Chem., 285, 33315-33323.
    View publication on PubMed
Search for more literature for 1.8.4.12

Protein Variants

Protein Variants Comment Organism
U95C the mutant has a significantly decreased activity Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
L-methionine sulfone
-
 Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ MsrB1 is a zinc-containing protein Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-methionine (R)-sulfoxide + thioredoxin Mus musculus
-
 L-methionine + thioredoxin disulfide + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JLC3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dabsyl-L-methionine (R)-sulfoxide + dithiothreitol
-
 Mus musculus dabsyl-L-methionine + dithiothreitol disulfide + H2O
-
 ?
L-methionine (R)-sulfoxide + thioredoxin
-
 Mus musculus L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase B1
-
 Mus musculus
MSRB1
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
thioredoxin
-
 Mus musculus