Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.8.4.12 extracted from

  • Moskovitz, J.; Poston, J.M.; Berlett, B.S.; Nosworthy, N.J.; Szczepanowski, R.; Stadtman, E.R.
    Identification and characterization of a putative active site for peptide methionine sulfoxide reductase (MsrA) and its substrate stereospecificity (2000), J. Biol. Chem., 275, 14167-14172.
    View publication on PubMed
Search for more literature for 1.8.4.12

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-methionine (R)-sulfoxide + thioredoxin Homo sapiens Msr is specific for the R-isomer L-methionine + thioredoxin disulfide + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte polymorphonuclear Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-methyl 4-tolyl sulfoxide + thioredoxin
-
 Homo sapiens ?
-
 ?
dabsyl-L-methionine (R)-sulfoxide + thioredoxin FMsr is specific for the R-isomer Homo sapiens dabsyl-L-methionine + thioredoxin disulfide + H2O
-
 ?
L-methionine (R)-sulfoxide + thioredoxin Msr is specific for the R-isomer Homo sapiens L-methionine + thioredoxin disulfide + H2O
-
 ?
additional information substrate specificity Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
thioredoxin
-
 Homo sapiens