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Literature summary for 1.8.4.11 extracted from

  • Oien, D.B.; Osterhaus, G.L.; Lundquist, B.L.; Fowler, S.C.; Moskovitz, J.
    Caloric restriction alleviates abnormal locomotor activity and dopamine levels in the brain of the methionine sulfoxide reductase A knockout mouse (2010), Neurosci. Lett., 468, 38-41.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus Q9D6Y7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-methionine (S)-sulfoxide + 2 dithiothreitol
-
Mus musculus L-methionine + dithiothreitol disulfide + H2O
-
?

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase A
-
Mus musculus
MsrA
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Mus musculus

Cofactor

Cofactor Comment Organism Structure
dithiothreitol
-
Mus musculus

General Information

General Information Comment Organism
physiological function MsrA knockout mice exhibit altered locomotor activity and brain dopamine levels as function of age, caloric restriction has a neutralization effect on MsrA ablation Mus musculus