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Literature summary for 1.8.4.11 extracted from
- Alternative first exon splicing regulates subcellular distribution of methionine sulfoxide reductases (2006), BMC Mol. Biol., 7, 11.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| genomic structure, alternative splicing variants, overview | Drosophila melanogaster |
| genomic structure, alternative splicing variants, overview | Homo sapiens |
| genomic structure, alternative splicing variants, overview, expression of GFP-tagged and/or His-tagged mitochondrial and cytosolic MsrAs in CV-1 cells | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | isozyme MsrA3 | Homo sapiens | 5829 | - |
| cytosol | - |
Homo sapiens | 5829 | - |
| cytosol | - |
Drosophila melanogaster | 5829 | - |
| cytosol | splicing variant MsrA(S) | Mus musculus | 5829 | - |
| mitochondrion | - |
Homo sapiens | 5739 | - |
| mitochondrion | mitochondrial splicing variant MsrA | Mus musculus | 5739 | - |
| additional information | subcellular localization is regulated by alternative splicing, overview | Homo sapiens | - |
- |
| additional information | subcellular localization is regulated by alternative splicing, overview | Drosophila melanogaster | - |
- |
| additional information | subcellular localization is regulated by alternative splicing, overview | Mus musculus | - |
- |
| nucleus | - |
Homo sapiens | 5634 | - |
| nucleus | splicing variant MsrA(S) | Mus musculus | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | P08761 | gene Eip71CD or Eip28/29; alternative splicing variants, overview | - |
| Homo sapiens | - |
alternative splicing variants, overview | - |
| Homo sapiens | Q9UJ68 | isozyme MsrA3; alternative splicing variants, overview | - |
| Mus musculus | Q9D6Y7 | alternative splicing variants, overview | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
| kidney | - |
Mus musculus | - |
| liver | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-methionine-(S)-S-oxide + thioredoxin | stereospecific reduction | Homo sapiens | L-methionine + thioredoxin disulfide + H2O | - |
? |  |
| L-methionine-(S)-S-oxide + thioredoxin | stereospecific reduction | Mus musculus | L-methionine + thioredoxin disulfide + H2O | - |
? | |
| peptide-L-methionine-(S)-S-oxide + thioredoxin | stereospecific reduction | Drosophila melanogaster | peptide-L-methionine + thioredoxin disulfide + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ecdysone-induced protein 28/29 kDa | - |
Drosophila melanogaster |
| methionine sulfoxide reductase A | - |
Homo sapiens |
| methionine sulfoxide reductase A | - |
Drosophila melanogaster |
| methionine sulfoxide reductase A | - |
Mus musculus |
| MsrA | - |
Homo sapiens |
| MsrA | - |
Drosophila melanogaster |
| MsrA | - |
Mus musculus |
| peptide methionine sulfoxide reductase | - |
Drosophila melanogaster |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thioredoxin | - |
Drosophila melanogaster | |
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