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Literature summary for 1.8.4.11 extracted from

  • Tamburro, A.; Robuffo, I.; Heipieper, H.J.; Allocati, N.; Rotilio, D.; Di Ilio, C.; Favaloro, B.
    Expression of glutathione S-transferase and peptide methionine sulphoxide reductase in Ochrobactrum anthropi is correlated to the production of reactive oxygen species caused by aromatic substrates (2004), FEMS Microbiol. Lett., 241, 151-156.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information enzyme expression is induced, together with the glutathione S-transferase, by toxic concentrations of aromatic substrates such as phenol and 4-chlorophenol which cause production of reactive oxygen species Brucella anthropi

Localization

Localization Comment Organism GeneOntology No. Textmining
cell envelope associated Brucella anthropi 30313
-
cytoplasmic membrane inner or outer side Brucella anthropi
-
-
additional information subcellular distribution of the enzyme in cells grown on 4-chlorophenol Brucella anthropi
-
-
periplasmic space
-
 Brucella anthropi 42597
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Brucella anthropi detoxification enzyme ?
-
 ?
protein-L-methionine (S)-sulfoxide + thioredoxin Brucella anthropi enzyme provides protection against oxidative damage by reactive oxygen species and has a repair function for oxidized protein methionine residues protein-L-methionine + thioredoxin disulfide + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Brucella anthropi
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:4-chlorophenol-grown cell
-
 Brucella anthropi
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information detoxification enzyme Brucella anthropi ?
-
 ?
protein-L-methionine (S)-sulfoxide + thioredoxin
-
 Brucella anthropi protein-L-methionine + thioredoxin disulfide + H2O
-
 ?
protein-L-methionine (S)-sulfoxide + thioredoxin enzyme provides protection against oxidative damage by reactive oxygen species and has a repair function for oxidized protein methionine residues Brucella anthropi protein-L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
MsrA
-
 Brucella anthropi
peptide methionine sulphoxide reductase
-
 Brucella anthropi