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Literature summary for 1.8.1.B1 extracted from

  • Cao, Y.; Zhao, B.; Han, Y.; Zhang, J.; Li, X.; Qiu, C.; Wu, X.; Hong, Y.; Ai, D.; Lin, J.; Fu, Z.
    Gene gun bombardment with DNA-coated golden particles enhanced the protective effect of a DNA vaccine based on thioredoxin glutathione reductase of Schistosoma japonicum (2013), BioMed Res. Int., 2013, 952416.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information the recombinant plasmid DNA vaccine pVAX1/SjTGR lowers enzymatic activity in vivo and in vitro Schistosoma japonicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 GSH + NADP+ Schistosoma japonicum
-
GSSG + NADPH + H+
-
?
thioredoxin + NADP+ Schistosoma japonicum
-
thioredoxin disulfide + NADPH + H+
-
?

Organism

Organism UniProt Comment Textmining
Schistosoma japonicum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 GSH + NADP+
-
Schistosoma japonicum GSSG + NADPH + H+
-
?
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH + H+
-
Schistosoma japonicum 2-nitro-5-thiobenzoate + NADP+
-
?
thioredoxin + NADP+
-
Schistosoma japonicum thioredoxin disulfide + NADPH + H+
-
?

Synonyms

Synonyms Comment Organism
TGR
-
Schistosoma japonicum

Cofactor

Cofactor Comment Organism Structure
FAD
-
Schistosoma japonicum
NADP+
-
Schistosoma japonicum