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Literature summary for 1.8.1.9 extracted from

  • Eriksson, S.E.; Prast-Nielsen, S.; Flaberg, E.; Szekely, L.; Arner, E.S.
    High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy (2009), Free Radic. Biol. Med., 47, 1661-1671.
    View publication on PubMed
Search for more literature for 1.8.1.9

Inhibitors

Inhibitors Comment Organism Structure
1-chloro-2,4-dinitrobenzene
-
 Homo sapiens
1-chloro-2,4-dinitrobenzene
-
 Rattus norvegicus
auranofin
-
 Homo sapiens
auranofin
-
 Rattus norvegicus
cisplatin
-
 Homo sapiens
cisplatin
-
 Rattus norvegicus
juglone
-
 Homo sapiens
juglone
-
 Rattus norvegicus
menadione
-
 Homo sapiens
menadione
-
 Rattus norvegicus
oxaliplatin
-
 Homo sapiens
oxaliplatin
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 SDS-PAGE Homo sapiens
55000
-
 SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16881
-
-
Rattus norvegicus O89049
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Homo sapiens
? x * 55000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
thioredoxin reductase 1
-
 Homo sapiens
thioredoxin reductase 1
-
 Rattus norvegicus
TrxR1
-
 Homo sapiens
TrxR1
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Homo sapiens
NADPH
-
 Rattus norvegicus