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Literature summary for 1.8.1.7 extracted from

  • Tano, T.; Ishii, K.; Sugio, T.; Imai, K.
    A NADPH:glutathione oxidoreductase isolated from Thiobacillus thiooxidans (1976), Agric. Biol. Chem., 40, 1879-1880.
No PubMed abstract available
Search for more literature for 1.8.1.7

Inhibitors

Inhibitors Comment Organism Structure
AgNO3
-
 Acidithiobacillus thiooxidans
Hg2+
-
 Acidithiobacillus thiooxidans
mercuric sulfate
-
 Acidithiobacillus thiooxidans
p-chloromercuribenzoate
-
 Acidithiobacillus thiooxidans

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Acidithiobacillus thiooxidans 5737
-

Organism

Organism UniProt Comment Textmining
Acidithiobacillus thiooxidans
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Acidithiobacillus thiooxidans

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.331
-
 purified enzyme Acidithiobacillus thiooxidans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GSSG + NADPH methylene blue and L-cystine slowly Acidithiobacillus thiooxidans glutathione + NADP+
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
 irreversible denaturation above, complete loss of activity after 40 min Acidithiobacillus thiooxidans
50
-
 10 min, complete loss of activity Acidithiobacillus thiooxidans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Acidithiobacillus thiooxidans

pH Stability

pH Stability pH Stability Maximum Comment Organism
6 8 unstable below and above Acidithiobacillus thiooxidans

Cofactor

Cofactor Comment Organism Structure
NADH low activity with NADH Acidithiobacillus thiooxidans
NADPH
-
 Acidithiobacillus thiooxidans