Application | Comment | Organism |
---|---|---|
medicine | the enzyme is sensitive to free radical generating antituberculosis drugs and may be useful target for new drug development | Mycobacterium tuberculosis variant bovis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
mycothione + NADPH | Mycobacterium tuberculosis variant bovis | the enzyme is involved in mycothiol metabolism. Mycothiol may play an important role in the survival and adaption of mycobacteria to oxidative stress caused by normal metabolism, ir induced by the action of anti-tubercular drugs | mycothiol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis variant bovis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | gene is actively transcribed during logarithmic growth | Mycobacterium tuberculosis variant bovis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
mycothione + NADPH | the enzyme is involved in mycothiol metabolism. Mycothiol may play an important role in the survival and adaption of mycobacteria to oxidative stress caused by normal metabolism, ir induced by the action of anti-tubercular drugs | Mycobacterium tuberculosis variant bovis | mycothiol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NADPH-dependent mycothiol reductase | - |
Mycobacterium tuberculosis variant bovis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mycobacterium tuberculosis variant bovis |