Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cytochrome c551 | noncompetitive inhibitor of nitric oxide reduction when menaquinol is used as an electron donor | Schinkia azotoformans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0045 | - |
cytochrome c551 | pH and temperature not specified in the publication | Schinkia azotoformans | |
0.141 | - |
juglone | pH and temperature not specified in the publication | Schinkia azotoformans | |
0.256 | - |
Plumbagin | pH and temperature not specified in the publication | Schinkia azotoformans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
copper | the enzyme contains a CuA center in its small subunit | Schinkia azotoformans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schinkia azotoformans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no activity with lapachol, reduced horse heart cytochrome c, cytochrome c550, and cytochrome c552 | Schinkia azotoformans | ? | - |
? | |
nitric oxide + cytochrome c551 | the menaquinol pathway has a 4fold greater maximal activity than the pathway via cytochrome c551 | Schinkia azotoformans | ? | - |
? | |
nitric oxide + juglone | - |
Schinkia azotoformans | ? | - |
? | |
nitric oxide + menaquinol | the menaquinol pathway has a 4fold greater maximal activity than the pathway via cytochrome c551 | Schinkia azotoformans | nitrous oxide + menaquinone + H2O | - |
? | |
nitric oxide + plumbagin | - |
Schinkia azotoformans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
menaquinol-dependent nitric oxide reductase | - |
Schinkia azotoformans |
NO reductase | - |
Schinkia azotoformans |
qCuANOR | - |
Schinkia azotoformans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
41 | - |
nitric oxide | using cytochrome c551 as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans | |
118 | - |
nitric oxide | using juglone as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans | |
150 | - |
nitric oxide | using plumbagin as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans | |
153 | - |
nitric oxide | using menaquinol as electron donor, pH and temperature not specified in the publication | Schinkia azotoformans |
General Information | Comment | Organism |
---|---|---|
physiological function | the ability of qCuANOR to accept electrons from both menaquinol and cytochrome c551 may be related to the regulation of the rate of NO reduction especially as a defense mechanism of B. azotoformans against the toxicity of NO. The menaquinol pathway, which has a 4-fold greater maximal activity than the pathway via cytochrome c551, is used for NO detoxification, whereas electron donation via the endogenous cytochrome c involves the cytochrome b6f complex serving the bioenergetic needs of the organism | Schinkia azotoformans |