Literature summary for 1.7.3.3 extracted from

Sundy, J.S.; Ganson, N.J.; Kelly, S.J.; Scarlett, E.L.; Rehrig, C.D.; Huang, W.; Hershfield, M.S.
Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout (2007), Arthritis Rheum., 56, 1021-1028.

Search for more literature for 1.7.3.3

Application

Application	Comment	Organism
medicine	the enzyme might be useful in the treatment of patients with refractory gout, overview	Sus scrofa

Protein Variants

Protein Variants	Comment	Organism
additional information	the recombinantly expressed porcine enzyme, with a C-terminal sequence from baboon uricase, is applicated to patients with refractory gout, due to a mutation in the uricase gene, by intravenous injection in a PEG-bound form, pharmacokinetics and pharmacodynamics, safety, and efficacy of the treatment in a clinical trial, overview	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	P16164	-	-

Synonyms

Synonyms	Comment	Organism
uricase	-	Sus scrofa

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Release 2023.1 (January 2023)