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Literature summary for 1.7.2.6 extracted from

  • Kostera, J.; McGarry, J.; Pacheco, A.
    Enzymatic interconversion of ammonia and nitrite: The right tool for the job (2010), Biochemistry, 49, 8546-8553.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information in the presence of Ru(NH3)2+ and Ru(NH3)3+ at ratios exceeding 200:1, HAO exhibits no detectable Ru(NH3)2+-NO2- oxidoreductase activity Nitrosomonas europaea

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hydroxylamine + ferricytochrome c + H2O Nitrosomonas europaea
-
nitrite + ferrocytochrome c + H+
-
ir

Organism

Organism UniProt Comment Textmining
Nitrosomonas europaea
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hydroxylamine + ferricytochrome c + H2O
-
Nitrosomonas europaea nitrite + ferrocytochrome c + H+
-
ir
hydroxylamine + reduced methyl viologen + H+
-
Nitrosomonas europaea NH4+ + oxidized methyl viologen + H2O
-
ir
hydroxylamine + Ru(NH3)63+ + H+
-
Nitrosomonas europaea nitric oxide + Ru(NH3)62+ + H+
-
ir
additional information HAO does not catalyze the disproportionation of hydroxylamine, despite the thermodynamic favorability of such a process, and the apparent opportunity presented by the HAO structure Nitrosomonas europaea ?
-
?
nitrite + reduced methyl viologen + H+ HAO acts like a cytochrome c nitrite reductase, which catalyzes the six-electron reduction of nitrite to NH4+ by reduced methyl viologen Nitrosomonas europaea NH4+ + oxidized methyl viologen + H2O
-
?

Synonyms

Synonyms Comment Organism
HAO
-
Nitrosomonas europaea