Literature summary for 1.7.2.2 extracted from

Shahid, S.; Ali, M.; Legaspi-Humiston, D.; Wilcoxen, J.; Pacheco, A.A.
A kinetic investigation of the early steps in cytochrome c nitrite reductase (ccNiR)-catalyzed reduction of nitrite (2021), Biochemistry, 60, 2098-2115 .

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Organism

Organism	UniProt	Comment	Textmining
Shewanella oneidensis	Q8EAC7	-	-

Synonyms

Synonyms	Comment	Organism
ccNiR	-	Shewanella oneidensis
cytochrome c nitrite reductase	-	Shewanella oneidensis
cytochrome c-552	-	Shewanella oneidensis
NrfA	-	Shewanella oneidensis

General Information

General Information	Comment	Organism
metabolism	reduction of nitrite-loaded ccNiR by N,N,N',N'-tetramethyl-pphenylenediamine generates a transient intermediate, identified as FeH1II(NO2-), where FeH1 represents the ccNiR active site. FeH1II(NO2-) accumulates rapidly and is then more slowly converted to the two-electron-reduced moiety [FeH1NO]7. ccNiR is not reduced beyond the [FeH1NO]7 state. The midpoint potentials for sequential reduction of FeH1III(NO2-) to FeH1II(NO2-) and then to [FeH1NO]7 are 130 and 370 mV versus the standard hydrogen electrode, respectively. With weak reductants, free NO radical is released from nitrite-loaded ccNiR	Shewanella oneidensis

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Release 2023.1 (January 2023)