Literature summary for 1.6.5.2 extracted from

Rougee, L.R.; Riches, Z.; Berman, J.M.; Collier, A.C.
The ontogeny and population variability of human hepatic NADPH dehydrogenase quinone oxido-reductase 1 (NQO1) (2016), Drug Metab. Dispos., 44, 967-974 .

Search for more literature for 1.6.5.2

Application

Application	Comment	Organism
medicine	protein expression but not activity of NQO1 is weakly negatively correlated with age. No sex differences are observed for either protein expression or activity and for ethnicity. Caucasians have greater NQO1 activity than Asians. Overweight children have statistically significantly higher NQO1 activity as compared with ideal weight children	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Homo sapiens	P15559	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-
liver	protein expression but not activity of NQO1 is weakly negatively correlated with age. No sex differences are observed for either protein expression or activity and for ethnicity. Caucasians have greater NQO1 activity than Asians. Overweight children have statistically significantly higher NQO1 activity as compared with ideal weight children	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
NQO1	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	protein expression but not activity of NQO1 is weakly negatively correlated with age. No sex differences are observed for either protein expression or activity and for ethnicity. Caucasians have greater NQO1 activity than Asians. Overweight children have statistically significantly higher NQO1 activity as compared with ideal weight children	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)