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Literature summary for 1.6.5.2 extracted from

  • Chen, C.Y.; Blumberg, J.B.
    In vitro activity of almond skin polyphenols for scavenging free radicals and inducing quinone reductase (2008), J. Agric. Food Chem., 56, 4427-4434.
    View publication on PubMed
Search for more literature for 1.6.5.2

Activating Compound

Activating Compound Comment Organism Structure
beta-naphthoflavone
-
 Mus musculus
isorhamnetin
-
 Mus musculus
additional information almond skin polyphenol extracted with methanol increases quinone reductase activity. Combining almond skin polyphenol extracted with methanol plus vitamin C results in a synergistic interaction Mus musculus
vitamin C
-
 Mus musculus

Application

Application Comment Organism
drug development in vitro, almond skin polyphenols act as antioxidants and induce quinone reductase activity, but these actions are dependent upon their dose, method of extraction, and interaction with antioxidant vitamins Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
additional information almond skin polyphenol extracted with agastrointestinal juice mimic decreases quinone reductase activity. Combining almond skin polyphenol extracted with agastrointestinal juice mimic plus vitamin C has an antagonistic effect Mus musculus
vitamin E
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hepa-1c1c7 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide + NAD(P)H
-
 Mus musculus reduced 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide + NAD(P)+
-
 ?

Synonyms

Synonyms Comment Organism
Quinone reductase
-
 Mus musculus