Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | microsomal enzyme: not inhibited by dicoumarol, lapachol and p-chloromercuribenzoate | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
microsomal enzyme, partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.039 | - |
activity in liver microsomes, reduction of menadione, cofactor NADPH | Rattus norvegicus |
0.041 | - |
activity in liver cytosol, reduction of menadione, cofactor NADH | Rattus norvegicus |
0.051 | - |
activity in liver cytosol, reduction of menadione, cofactor NADPH | Rattus norvegicus |
0.121 | - |
activity in liver cytosol, reduction of 2,6-dichlorophenolindophenol, cofactor NADPH | Rattus norvegicus |
0.128 | - |
activity in liver cytosol, reduction of 2,6-dichlorophenolindophenol, cofactor NADH | Rattus norvegicus |
0.153 | - |
activity in liver microsomes, reduction of menadione, cofactor NADH | Rattus norvegicus |
0.157 | - |
activity in liver microsomes, reduction of 2,6-dichlorophenolindophenol, cofactor NADPH | Rattus norvegicus |
0.63 | - |
activity in liver microsomes, reduction of 2,6-dichlorophenolindophenol, cofactor NADH | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-methyl-1,4-naphthoquinone + NAD(P)H | microsomal enzyme | Rattus norvegicus | 2-methyl-1,4-naphthoquinol + NAD(P)+ | - |
? | |
NAD(P)H + H+ + oxidized 2,6-dichlorophenolindophenol | microsomal enzyme | Rattus norvegicus | NAD(P)+ + reduced 2,6-dichlorophenolindophenol | - |
? |