BRENDA - Enzyme Database show
show all sequences of 1.6.5.10

Oxidative stress in tardive dyskinesia: Genetic association study and meta-analysis of NADPH quinine oxidoreductase 1 (NQO1) and superoxide dismutase 2 (SOD2, MnSOD) genes

Zai, C.C.; Tiwari, A.K.; Basile, V.; de Luca, V.; Mueller, D.J.; Voineskos, A.N.; Remington, G.; Meltzer, H.Y.; Lieberman, J.A.; Potkin, S.G.; Kennedy, J.L.; Prog. Neuropsychopharmacol. Biol. Psychiatry 34, 50-56 (2009)

Data extracted from this reference:

Application
Application
Commentary
Organism
medicine
Pro187Ser polymorphism in NQO1 has a limited role in the development of Tardive dyskinesia (a potentially irreversible side effect of antipsychotic medication treatment that occurs in approximately 25% of chronically treated schizophrenia patients)
Homo sapiens
Engineering
Amino acid exchange
Commentary
Organism
P187S
Pro187Ser polymorphism in NQO1 has a limited role in the development of Tardive dyskinesia (a potentially irreversible side effect of antipsychotic medication treatment that occurs in approximately 25% of chronically treated schizophrenia patients)
Homo sapiens
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Application (protein specific)
Application
Commentary
Organism
medicine
Pro187Ser polymorphism in NQO1 has a limited role in the development of Tardive dyskinesia (a potentially irreversible side effect of antipsychotic medication treatment that occurs in approximately 25% of chronically treated schizophrenia patients)
Homo sapiens
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
P187S
Pro187Ser polymorphism in NQO1 has a limited role in the development of Tardive dyskinesia (a potentially irreversible side effect of antipsychotic medication treatment that occurs in approximately 25% of chronically treated schizophrenia patients)
Homo sapiens
Other publictions for EC 1.6.5.10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743650
Brissos
Improving kinetic or thermody ...
Pseudomonas putida, Pseudomonas putida MET94
PLoS ONE
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Hervas
ArsH from the cyanobacterium S ...
Synechocystis sp.
Biochemistry
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Crosas
Novel alkenal/one reductase ac ...
Saccharomyces cerevisiae
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32-37
2011
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701035
Zai
Oxidative stress in tardive dy ...
Homo sapiens
Prog. Neuropsychopharmacol. Biol. Psychiatry
34
50-56
2009
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688840
Hong
The NADPH quinone reductase Md ...
Helicobacter hepaticus, Helicobacter hepaticus ATCC 51449
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Arsenic methylation capability ...
Homo sapiens
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Endo
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Gharavi
Role of nitric oxide in downre ...
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The 1.3 A crystal structure of ...
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27904-27913
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658899
Wang
An NADPH quinone reductase of ...
Helicobacter pylori
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Molecular cloning and characte ...
Kluyveromyces marxianus
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714140
Schlegel
Retention of NADPH-linked quin ...
Rattus norvegicus
Biochemistry
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11003-11011
1998
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Diatchuk
Inhibition of NADPH oxidase ac ...
Cavia porcellus, Homo sapiens
J. Biol. Chem.
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13292-13301
1997
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Hayashi
NADPH-specific quinone reducta ...
Escherichia coli
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1273
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1996
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Batot
Characterization of neutrophil ...
Homo sapiens
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1995
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Viljoen
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Isolation and characterization ...
Microcystis aeruginosa
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1985
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392827
Pupillo
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Pyridine nucleotide-linked deh ...
Cucurbita pepo, Zea mays
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Jagendorf
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Chloroplast TPNH diaphorase ...
Spinacia oleracea
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