Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + O2 | Homo sapiens | - |
? | - |
? | |
epinephrine + O2 | Homo sapiens | - |
? | - |
? | |
L-DOPA + O2 | Homo sapiens | - |
? | - |
? | |
norepinephrine + O2 | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Homo sapiens | - |
brain | - |
Homo sapiens | - |
heart | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
skeletal muscle | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + O2 | - |
Homo sapiens | ? | - |
? | |
epinephrine + O2 | - |
Homo sapiens | ? | - |
? | |
L-DOPA + O2 | - |
Homo sapiens | ? | - |
? | |
norepinephrine + O2 | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 37800, calculated from amino acid sequence | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Homo sapiens | |
NADH | - |
Homo sapiens | |
NADPH | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | renalase participates in the pathophysiological mechanism of cardiac dysfunction by down-regulating the activity of sympathetic nervous system and degrading the level of catecholamines. Renalase is strongly associated with type 1 diabetes, hypertension and ischemic diseases | Homo sapiens |