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Literature summary for 1.6.3.1 extracted from
- Characterization of N-glycosylation sites on the extracellular domain of NOX1/NADPH oxidase (2014), Free Radic. Biol. Med., 68, 196-204 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293 cells | Mus musculus |
| expressed in HEK-293 cells | Homo sapiens |
| expressed in HEK-293 cells | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Mus musculus | 16020 | - |
| membrane | - |
Homo sapiens | 16020 | - |
| membrane | - |
Rattus norvegicus | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADPH + H+ + O2 | Mus musculus | - |
NADP+ + H2O2 | - |
? |  |
| NADPH + H+ + O2 | Homo sapiens | - |
NADP+ + H2O2 | - |
? | |
| NADPH + H+ + O2 | Rattus norvegicus | - |
NADP+ + H2O2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Mus musculus |
| glycoprotein | - |
Homo sapiens |
| glycoprotein | - |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| colon | - |
Mus musculus | - |
| colon | - |
Homo sapiens | - |
| colon | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADPH + H+ + O2 | - |
Mus musculus | NADP+ + H2O2 | - |
? | |
| NADPH + H+ + O2 | - |
Homo sapiens | NADP+ + H2O2 | - |
? | |
| NADPH + H+ + O2 | - |
Rattus norvegicus | NADP+ + H2O2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 53000, deglycosylated enzyme, SDS-PAGE | Mus musculus |
| ? | x * 53000, deglycosylated enzyme, SDS-PAGE | Rattus norvegicus |
| ? | x * 65000, glycosylated enzyme, SDS-PAGE | Mus musculus |
| ? | x * 65000, glycosylated enzyme, SDS-PAGE | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NADPH oxidase | - |
Mus musculus |
| NADPH oxidase | - |
Homo sapiens |
| NADPH oxidase | - |
Rattus norvegicus |
| NOX1 | catalytic subunit | Mus musculus |
| NOX1 | catalytic subunit | Homo sapiens |
| NOX1 | catalytic subunit | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Mus musculus | |
| NADPH | - |
Homo sapiens | |
| NADPH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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