Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + H+ + O2 | - |
Rattus norvegicus | NADP+ + H2O2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Rattus norvegicus | |
heme | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | losartan administration significantly reduces oxidative stress generation by decreasing NAD(P)H oxidase expression | down |
Rattus norvegicus | a strong upregulation of NAD(P)H oxidase subunits p22phox and p47phox is observed in the hypertensive kidney of aortic coarcted rats | up |