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Literature summary for 1.6.3.1 extracted from

  • McCaffrey, R.L.; Schwartz, J.T.; Lindemann, S.R.; Moreland, J.G.; Buchan, B.W.; Jones, B.D.; Allen, L.A.
    Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis (2010), J. Leukoc. Biol., 88, 791-805.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.6.3.1

Inhibitors

Inhibitors Comment Organism Structure
additional information Francisella tularensis inhibits NADPH oxidase activity in a cell-free assay; the regulatory factor fevR is essential for NADPH oxidase inhibition, whereas iglI and iglJ, candidate secretion system effectors, and the acid phosphatase acpA are not Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADPH + H+ + O2 Homo sapiens
-
 NADP+ + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + H+ + O2
-
 Homo sapiens NADP+ + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
NADPH oxidase
-
 Homo sapiens