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Literature summary for 1.6.3.1 extracted from

  • Ben Mkaddem, S.; Pedruzzi, E.; Werts, C.; Coant, N.; Bens, M.; Cluzeaud, F.; Goujon, J.; Ogier-Denis, E.; Vandewalle, A.
    Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury (2010), Cell Death Differ., 17, 1474-1485.
    View publication on PubMed
Search for more literature for 1.6.3.1

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 NOX4 spliced isoform, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-
renal tubule epithelium
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
NAD(P)H oxidase 4
-
 Mus musculus
Nox4
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus ischemia/reperfusion injury stimulates the expression of a 28000 Da NOX4 spliced isoform up

General Information

General Information Comment Organism
physiological function the 28000 Da NOX4 isoform has a key role in toll-like receptor 4-mediated apoptosis during renal ischemia/reperfusion injury. NOX4 controls Jun N-terminal kinase-mediated renal tubule cell apoptosis induced by hypoxia Mus musculus