Literature summary for 1.6.3.1 extracted from

Izakovicova Holla, L.; Kankova, K.; Znojil, V.
Haplotype analysis of the NADPH oxidase p22 gene in patients with bronchial asthma (2008), Int. Arch. Allergy Immunol., 148, 73-80.

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Application

Application	Comment	Organism
medicine	single nucleotide polymorphisms 242C/T and 640A/G in the gene encoding p22phox subunit of NAD(P)H oxidase are marginally significantly associated with asthma, but single nucleotide polymorphisms 640A/G shows a significant association with sensitization to two allergens tested. Haplotype 930G/242T/640A is associated with an increased risk of asthma	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	single nucleotide polymorphisms 242C/T and 640A/G in the gene encoding p22phox subunit of NAD(P)H oxidase are marginally significantly associated with asthma, but single nucleotide polymorphisms 640A/G shows a significant association with sensitization to two allergens tested. Haplotype 930G/242T/640A is associated with an increased risk of asthma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	patients with bronchial asthma	-

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Release 2023.1 (January 2023)