Cloned (Comment) | Organism |
---|---|
expression in transformed strains | Saccharomyces cerevisiae |
expression in transformed strains of Saccharomyces cerevisiae | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | heterologously expressed native and truncated protein | Homo sapiens | 5829 | - |
cytosol | heterologously expressed native and truncated protein | Saccharomyces cerevisiae | 5829 | - |
microsome | heterologously expressed native and truncated protein | Homo sapiens | - |
- |
microsome | heterologously expressed native and truncated protein | Saccharomyces cerevisiae | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
75000 | - |
truncated protein | Saccharomyces cerevisiae |
78000 | - |
- |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces cerevisiae | involved in the sterol biosynthesis pathways | ? | - |
? | |
additional information | Saccharomyces cerevisiae JL20 | involved in the sterol biosynthesis pathways | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Saccharomyces cerevisiae | - |
JL20 strain | - |
Saccharomyces cerevisiae JL20 | - |
JL20 strain | - |
Renatured (Comment) | Organism |
---|---|
native or truncated protein reconstituts ergosterol biosynthesis when added to a cell-free system, as well as reconstitution of activity with purified Saccharomyces cerevisiae CYP61, sterol 22-desaturase, Candida albicans and human CYP51 | Saccharomyces cerevisiae |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
24.3 | - |
purified truncated protein | Saccharomyces cerevisiae |
36 | - |
purified truncated protein | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | involved in the sterol biosynthesis pathways | Saccharomyces cerevisiae | ? | - |
? | |
additional information | involved in the sterol biosynthesis pathways | Saccharomyces cerevisiae JL20 | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens | |
NADPH | - |
Saccharomyces cerevisiae |