Literature summary for 1.6.2.2 extracted from

Nikiforova, A.B.; Saris, N.E.; Kruglov, A.G.
External mitochondrial NADH-dependent reductase of redox cyclers VDAC1 or Cyb5R3? (2014), Free Radic. Biol. Med., 74, 74-84 .

Search for more literature for 1.6.2.2

Inhibitors

Inhibitors	Comment	Organism	Structure
6-Propyl-2-thiouracil	about 20% residual activity at 0.009 mM	Rattus norvegicus
ebselen	almost complete inhibition at 0.02 mM	Rattus norvegicus
Mersalyl	complete inhibition at 1.0 mM	Rattus norvegicus
p-chloromercuribenzoate	complete inhibition at 0.4 mM	Rattus norvegicus
quercetin	about 20% residual activity at 0.02 mM	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
NADH + ferricytochrome b5	Rattus norvegicus	-	NAD+ + H+ + ferrocytochrome b5	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NADH + ferricytochrome b5	-	Rattus norvegicus	NAD+ + H+ + ferrocytochrome b5	-	?
NADH + ferricytochrome c	-	Rattus norvegicus	NAD+ + H+ + ferrocytochrome c	-	?

Synonyms

Synonyms	Comment	Organism
CYB5R3	-	Rattus norvegicus

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Release 2023.1 (January 2023)