Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | bound | Oncorhynchus mykiss | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome b5 + NADH | Canis lupus familiaris | - |
2 ferrocytochrome b5 + NAD+ + H+ | - |
? | |
2 ferricytochrome b5 + NADH | Equus caballus | - |
2 ferrocytochrome b5 + NAD+ + H+ | - |
? | |
2 ferricytochrome b5 + NADH | Oncorhynchus mykiss | - |
2 ferrocytochrome b5 + NAD+ + H+ | - |
? | |
2 ferricytochrome b5 + NADH | Felis sp. | - |
2 ferrocytochrome b5 + NAD+ + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Equus caballus | - |
- |
- |
Felis sp. | - |
- |
- |
Oncorhynchus mykiss | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Canis lupus familiaris | - |
erythrocyte | - |
Equus caballus | - |
erythrocyte | - |
Felis sp. | - |
erythrocyte | nucleated | Oncorhynchus mykiss | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
enzyme activity in erythrocytes of mammalian enzymes and rainbow trout, overview | Canis lupus familiaris |
additional information | - |
enzyme activity in erythrocytes of mammalian enzymes and rainbow trout, overview | Equus caballus |
additional information | - |
enzyme activity in erythrocytes of mammalian enzymes and rainbow trout, overview | Felis sp. |
additional information | - |
enzyme activity in erythrocytes of rainbow trout compared to mammalian enzymes, overview | Oncorhynchus mykiss |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome b5 + NADH | - |
Canis lupus familiaris | 2 ferrocytochrome b5 + NAD+ + H+ | - |
? | |
2 ferricytochrome b5 + NADH | - |
Equus caballus | 2 ferrocytochrome b5 + NAD+ + H+ | - |
? | |
2 ferricytochrome b5 + NADH | - |
Oncorhynchus mykiss | 2 ferrocytochrome b5 + NAD+ + H+ | - |
? | |
2 ferricytochrome b5 + NADH | - |
Felis sp. | 2 ferrocytochrome b5 + NAD+ + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cb5r | - |
Canis lupus familiaris |
cb5r | - |
Equus caballus |
cb5r | - |
Oncorhynchus mykiss |
cb5r | - |
Felis sp. |
NADH-dependent cytochrome b5 reductase | - |
Canis lupus familiaris |
NADH-dependent cytochrome b5 reductase | - |
Equus caballus |
NADH-dependent cytochrome b5 reductase | - |
Oncorhynchus mykiss |
NADH-dependent cytochrome b5 reductase | - |
Felis sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | dependent on | Canis lupus familiaris | |
NADH | dependent on | Equus caballus | |
NADH | dependent on | Oncorhynchus mykiss | |
NADH | dependent on | Felis sp. |
General Information | Comment | Organism |
---|---|---|
metabolism | the quantity of methemoglobin is kept in balance by an efficient redox system within erythrocytes involving the enzyme, overview | Oncorhynchus mykiss |
physiological function | methemoglobin in rainbow trout erythrocytes can be reduced by NADH-dependent cytochrome b5 reductase, i.e. CB5R, or NADPH-dependent methemoglobin reductase. The nucleated red blood cells of rainbow trout use membrane-bound CB5R to reduce methemoglobin | Oncorhynchus mykiss |