Inhibitors | Comment | Organism | Structure |
---|---|---|---|
BAL0030543 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Staphylococcus aureus | |
BAL0030543 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus mitis | |
BAL0030543 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus pneumoniae | |
BAL0030544 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Staphylococcus aureus | |
BAL0030544 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus mitis | |
BAL0030544 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus pneumoniae | |
BAL0030545 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Staphylococcus aureus | |
BAL0030545 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus mitis | |
BAL0030545 | a dihydrophthalazine inhibitor with antibacterial activity, overview | Streptococcus pneumoniae | |
trimethoprim | - |
Staphylococcus aureus | |
trimethoprim | - |
Streptococcus mitis | |
trimethoprim | - |
Streptococcus pneumoniae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
methicillin-sensitive and -resistant strains | - |
Streptococcus mitis | - |
methicillin-sensitive and -resistant strains | - |
Streptococcus pneumoniae | - |
methicillin-sensitive and -resistant strains | - |
Synonyms | Comment | Organism |
---|---|---|
DHFR | - |
Staphylococcus aureus |
DHFR | - |
Streptococcus pneumoniae |
DHFR | - |
Streptococcus mitis |
General Information | Comment | Organism |
---|---|---|
physiological function | dihydrofolate reductase is an enzyme with a pivotal role in the synthesis of intracellular tetrahydrofolic acid, which is essential in the synthesis of purines, some amino acids, and thymidine. DHFR is the sole source of tetrahydrofolic acid | Staphylococcus aureus |
physiological function | dihydrofolate reductase is an enzyme with a pivotal role in the synthesis of intracellular tetrahydrofolic acid, which is essential in the synthesis of purines, some amino acids, and thymidine. DHFR is the sole source of tetrahydrofolic acid | Streptococcus pneumoniae |
physiological function | dihydrofolate reductase is an enzyme with a pivotal role in the synthesis of intracellular tetrahydrofolic acid, which is essential in the synthesis of purines, some amino acids, and thymidine. DHFR is the sole source of tetrahydrofolic acid | Streptococcus mitis |