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Literature summary for 1.5.1.3 extracted from

  • Remy, I.; Campbell-Valois, F.X.; Michnick, S.W.
    Detection of protein-protein interactions using a simple survival protein-fragment complementation assay based on the enzyme dihydrofolate reductase (2007), Nat. Protoc., 2, 2120-2125.
    View publication on PubMed

Application

Application Comment Organism
analysis development of a survival protein-fragment complementation assay based on dihydrofolate reductase. Proteins of interest are fused to complementary fragments of dihydrofolate reductase. If the proteins of interst interact physically, the dihydrofolate complementary fragments are brought together and fold into the native structure, reconstituting its activity Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus P00375
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