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Literature summary for 1.5.1.3 extracted from
- Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase (2008), Malar. J., 7, 72.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | identification of synonymous and non-synonymous single nucleotide polymorphisms in the Plasmodium vivax dihydrolfolate reductase gene isolated from patients from Colombia, India, Indonesia, Papua New Guinea, Sri Lanka, thailand, and Vanuatu. The double mutant 58R/117N allele has evolved from several origins, because the 58R is encoded by at least 3 different codons. The triple 58R/61M/117T and quadruple 57L/61M/117T/173F, 57I/58R/61M/117T and 57L/58R/61M/117T mutant alleles had at least three independent origins in Thailand, Indonesia, and Papua New Guinea/Vanuatu | Plasmodium vivax |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium vivax | - |
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