Literature summary for 1.5.1.3 extracted from

Fogel, G.B.; Cheung, M.; Pittman, E.; Hecht, D.
Modeling the inhibition of quadruple mutant Plasmodium falciparum dihydrofolate reductase by pyrimethamine derivatives (2008), J. Comput. Aided Mol. Des., 22, 29-38.

Search for more literature for 1.5.1.3

Application

Application	Comment	Organism
drug development	modeling of 32 pyrimethamine derivatives into the active site of dihydrofolate reductase obtained from crystal structure 1J3K.pdb. Evaluation of predicted binding modes and key protein-ligand interactions	Plasmodium falciparum

Crystallization (Commentary)

Crystallization (Comment)	Organism
modeling of 32 pyrimethamine derivatives into the active site of dihydrofolate reductase obtained from crystal structure 1J3K.pdb. Evaluation of predicted binding modes and key protein-ligand interactions	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	-	-	-

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Release 2023.1 (January 2023)