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Literature summary for 1.5.1.3 extracted from

  • Shrimpton, P.; Mullaney, A.; Allemann, R.K.
    Functional role for Tyr 31 in the catalytic cycle of chicken dihydrofolate reductase (2003), Proteins, 51, 216-223.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Gallus gallus P00378
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7,8-dihydrofolate + NADPH water can serve as the Bronsted acid for the protonation of N5 of dihydrofolate during DHFR catalyzed reduction Gallus gallus 5,6,7,8-tetrahydrofolate + NADP+
-
?

Synonyms

Synonyms Comment Organism
DHFR
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Gallus gallus