Literature summary for 1.5.1.20 extracted from

Sun, D.F.; Weng, Y.R.; Chen, Y.X.; Lu, R.; Wang, X.; Fang, J.Y.
Knock-down of methylenetetrahydrofolate reductase reduces gastric cancer cell survival: An in vitro study (2008), Cell Biol. Int., 32, 879-887.

Search for more literature for 1.5.1.20

Application

Application	Comment	Organism
medicine	MTHFR inhibition may be a novel anticancer approach	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	inhibiting MTHFR with either antisense or siRNA decreases the viability of methionine-dependent transformed gastric cancer cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
MKN-45 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5,10-methylenetetrahydrofolate + reduced acceptor	-	Homo sapiens	5-methyltetrahydrofolate + oxidized acceptor	-	?

Synonyms

Synonyms	Comment	Organism
methylenetetrahydrofolate reductase	-	Homo sapiens
MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)