Literature summary for 1.5.1.20 extracted from

Siraj, A.K.; Ibrahim, M.; Al-Rasheed, M.; Bu, R.; Bavi, P.; Jehan, Z.; Abubaker, J.; Murad, W.; Al-Dayel, F.; Ezzat, A.; El-Solh, H.; Uddin, S.; Al-Kuraya, K.
Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East (2007), Ann. Hematol., 86, 887-895.

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Protein Variants

Protein Variants	Comment	Organism
additional information	C677T and A1298C gene polymorphisms are associated with reduced enzyme activity, thereby making MTHFR polymorphisms a potential candidate as a cancer-predisposing factor, they may be associated with the individual susceptibility to develop diffuse large B cell lymphoma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymph node	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
methylenetetrahydrofolate reductase	-	Homo sapiens
MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)